Licorice Root Extract by BioMatrix supports the adrenal glands when cortisol levels are low. A primary compound in licorice root is glycyrrhizin (a substance that has a molecular structure similar to corticosteroids). As such, licorice root aids in hypoadrenalism by partially blocking the enzyme that converts cortisol to cortisone, thus sparing cortisol. BioMatrix licorice root is 100% organically grown and harvested. A high-pressure liquid chromatography test of the plant is performed to determine the peak of botanical harvest. The compound is water-extracted within days of the harvest. Glycyrrhizin has been shown to improve headaches, low sex drive, anxiety, moodiness, swollen breasts, water retention, PMS symptoms, blood sugar control, and support hormone balance. Warnings: Contraindicated in: high blood pressure, heart failure, kidney disease, liver cirrhosis and cholestatic liver disorders.