When I first started taking the Bioactive Carbon Iodine I needed to break the tablets in 1/4 pieces because of the detox symptoms it created. I slowly worked myself up to 2 tablets a day. I was advised to take 4 a day, I did for a bit, but being short on $$$ I decided to save money and use up another brand of iodine, which I had on hand, rather than taking 2 more tablets of the Bioactive Carbon Iodine. Well, this other brand of iodine made my body unhappy to the point that I decided it would be better to take less than to frustrate my body so. So I continued with the two tablets for a while. There was lots of work that needed to be done but I just didn't have good energy. Finally it dawned on me, perhaps more iodine would give me more energy. I again started taking 4 tablets a day of the Bioactive Carbon Iodine. After a few days I realized the depression I had been struggling with greatly improved and not long after that my energy also much improved! I am so thankful! And now when I start thinking I should "save $$$" I remember that to "save $$$" is to become inefficient!!!